LAHN: Laboratoire d'Analyse des Huiles Naturelles et du Safran

trans-4-thujanol

NATURAL (E)-(R)-4-THUJANOL PURE CRYSTAL (C10H18O, CAS 546-79-2).

Scientific papers & media

Scientific article (Elsevier). Natural crystalline fibers of (E)-(R)-4-thujanol: green production and X-ray structure (July 2022).

Perfumer&Flavorist+. Production of the 4-thujanol flavoring agent in crystal form (Dec. 2022).

Conference: « Distinguished speaker talks ». Dr. Denis RONTEIN: Production of natural (E)-(R)-4-thujanol, in a crystal helix structure.  (Nov. 2023).

The pure and natural (E)-(R)-4-thujanol crystal is a product intended for scientific research. (E)-(R)-4-thujanol is proposed (1) as an analytical standard, (2) as an analogue of menthol and (3) in agricultural science. 

1. The (E)-(R)-4-thujanol is proposed as an analytical standard. (E)-(R)-4-thujanol is the only one available on earth produced from a natural source and delivered under the chiral P-type helix structure (see link to publications on the left panel this page). 

2. (E)-(R)-4-thujanol is an analogue of menthol. It could be use with avantages in binary or eutectic systems to facilitate the crossing of active molecules through cells membranes. Example by replacing lidocaine/menthol, by lidocaine/thujanol.

3. The (E)-(R)-4-thujanol has also bioactive properties in agricultural and forestry sciences (repellent of bark beetle and attractor of workers bees in sunflower).

The  pure (E)-(R)-4-thujanol crystal is stable at room temperature and can be shipped over the planet easily.

Its price is high but should not discourage the search for new applications. Indeed, the industrialization of crystallization can lead to a very important reduction of costs. Currently the cost is linked to the research that was implemented for this innovation.

See the table below for chemical identification and properties.

Parameters
Description
Resume
PURE AND NATURAL CRYSTAL OF (E)-(R)-4-THUJANOL ON SALE ON THIS WEBSITE (click below)
Identification numbers
CAS N° 546-79-2
Synonyms
4-Thujanol, trans-4-Thujanol, 4-Sabinene Hydrate, trans-4-Sabinene Hydrate, (E)-(R)-4-Sabinene Hydrate, Thujyl alcohol.
Food additive
FEMA N° 3239. Savors: fresh minty thyme.
Crystal structure
Monoclinic C2, chiral P-type helix. CCDC database number: 2144069
Crystal melting point
Tm: 60 °C
Publication
https://doi.org/10.1016/j.indcrop.2022.115451